Human WDR65 (CFAP57) activation kit by CRISPRa

CAT#: GA115710

CFAP57 CRISPRa kit - CRISPR gene activation of human cilia and flagella associated protein 57

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CFAP57
• Locus ID: 149465
• Kit Components:

  GA115710G1, CFAP57 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115710G2, CFAP57 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115710G3, CFAP57 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001167965, NM_001167966, NM_001195831, NM_152498, NR_030778
• Synonyms: VWS2; WDR65
• Summary: This protein encoded by this gene belongs to the WD repeat-containing family of proteins, which function in the formation of protein-protein complexes in a variety of biological pathways. This family member is thought to function in craniofacial development, possibly in the fusion of lip and palate. A missense mutation in this gene is associated with Van der Woude syndrome 2. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]