Human PPP1R1C activation kit by CRISPRa

CAT#: GA115784

PPP1R1C CRISPRa kit - CRISPR gene activation of human protein phosphatase 1 regulatory inhibitor subunit 1C

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PPP1R1C
• Locus ID: 151242
• Kit Components:

  GA115784G1, PPP1R1C gRNA vector 1 in pCas-Guide-CRISPRa

  GA115784G2, PPP1R1C gRNA vector 2 in pCas-Guide-CRISPRa

  GA115784G3, PPP1R1C gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001080545, NM_001261424, NM_001261425, NR_048566, NR_048567
• Synonyms: IPP5
• Summary: Protein phosphatase-1 (PP1) is a major serine/threonine phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or regulate its function. PPP1R1C belongs to a group of PP1 inhibitory subunits that are themselves regulated by phosphorylation (Wang et al., 2008 [PubMed 18310074]). [supplied by OMIM, Feb 2010]