Human H2BFWT activation kit by CRISPRa

CAT#: GA115982

H2BFWT CRISPRa kit - CRISPR gene activation of human H2B histone family member W, testis specific

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: H2BFWT
• Locus ID: 158983
• Kit Components:

  GA115982G1, H2BFWT gRNA vector 1 in pCas-Guide-CRISPRa

  GA115982G2, H2BFWT gRNA vector 2 in pCas-Guide-CRISPRa

  GA115982G3, H2BFWT gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001002916
• Synonyms: MGC148130; MGC148131
• Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the H2B histone family that is specifically expressed in sperm nuclei. A polymorphism in the 5' UTR of this gene is associated with male infertility. [provided by RefSeq, Oct 2015]