Human ALDH1L2 activation kit by CRISPRa

CAT#: GA116003

ALDH1L2 CRISPRa kit - CRISPR gene activation of human aldehyde dehydrogenase 1 family member L2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ALDH1L2
• Locus ID: 160428
• Kit Components:

  GA116003G1, ALDH1L2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116003G2, ALDH1L2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116003G3, ALDH1L2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001034173, NR_027752
• Synonyms: mtFDH
• Summary: This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2010]