Human CLEC14A activation kit by CRISPRa

CAT#: GA116018

CLEC14A CRISPRa kit - CRISPR gene activation of human C-type lectin domain containing 14A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CLEC14A
• Locus ID: 161198
• Kit Components:

  GA116018G1, CLEC14A gRNA vector 1 in pCas-Guide-CRISPRa

  GA116018G2, CLEC14A gRNA vector 2 in pCas-Guide-CRISPRa

  GA116018G3, CLEC14A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_175060
• Synonyms: C14orf27; CEG1; EGFR-5
• Summary: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting. [provided by RefSeq, Jan 2012]