Human TRPV3 activation kit by CRISPRa

CAT#: GA116051

TRPV3 CRISPRa kit - CRISPR gene activation of human transient receptor potential cation channel subfamily V member 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TRPV3
• Locus ID: 162514
• Kit Components:

  GA116051G1, TRPV3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116051G2, TRPV3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116051G3, TRPV3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001258205, NM_145068
• Synonyms: FNEPPK2; OLMS; VRL3
• Summary: This gene product belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. This gene lies in close proximity to another family member gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]