Human Prickle 2 (PRICKLE2) activation kit by CRISPRa

CAT#: GA116137

PRICKLE2 CRISPRa kit - CRISPR gene activation of human prickle planar cell polarity protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRICKLE2
• Locus ID: 166336
• Kit Components:

  GA116137G1, PRICKLE2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116137G2, PRICKLE2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116137G3, PRICKLE2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_198859, NM_001370528
• Synonyms: EPM5
• Summary: This gene encodes a homolog of Drosophila prickle. The exact function of this gene is not known, however, studies in mice suggest that it may be involved in seizure prevention. Mutations in this gene are associated with progressive myoclonic epilepsy type 5. [provided by RefSeq, Dec 2011]