Human MMAA activation kit by CRISPRa

CAT#: GA116145

MMAA CRISPRa kit - CRISPR gene activation of human metabolism of cobalamin associated A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MMAA
• Locus ID: 166785
• Kit Components:

  GA116145G1, MMAA gRNA vector 1 in pCas-Guide-CRISPRa

  GA116145G2, MMAA gRNA vector 2 in pCas-Guide-CRISPRa

  GA116145G3, MMAA gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_172250
• Synonyms: cblA
• Summary: The protein encoded by this gene is involved in the translocation of cobalamin into the mitochondrion, where it is used in the final steps of adenosylcobalamin synthesis. Adenosylcobalamin is a coenzyme required for the activity of methylmalonyl-CoA mutase. Defects in this gene are a cause of methylmalonic aciduria. [provided by RefSeq, Jul 2008]