Human DHX36 activation kit by CRISPRa

CAT#: GA116210

DHX36 CRISPRa kit - CRISPR gene activation of human DEAH-box helicase 36

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DHX36
• Locus ID: 170506
• Kit Components:

  GA116210G1, DHX36 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116210G2, DHX36 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116210G3, DHX36 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001114397, NM_020865
• Synonyms: DDX36; G4R1; MLEL1; RHAU
• Summary: This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3'-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]