Human IMMP1L activation kit by CRISPRa

CAT#: GA116265

IMMP1L CRISPRa kit - CRISPR gene activation of human inner mitochondrial membrane peptidase subunit 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IMMP1L
• Locus ID: 196294
• Kit Components:

  GA116265G1, IMMP1L gRNA vector 1 in pCas-Guide-CRISPRa

  GA116265G2, IMMP1L gRNA vector 2 in pCas-Guide-CRISPRa

  GA116265G3, IMMP1L gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001304274, NM_144981
• Synonyms: IMMP1; IMP1; IMP1-LIKE
• Summary: The mitochondrial inner membrane peptidase (IMP) complex generates mature, active proteins in the mitochondrial intermembrane space by proteolytically removing the mitochondrial targeting presequence of nuclear-encoded proteins. IMP1 and IMP2 (IMMP2L; MIM 605977) are the catalytic subunits of the IMP complex (Burri et al., 2005 [PubMed 15814844]). [supplied by OMIM, Sep 2008]