Human DHFRL1 (DHFR2) activation kit by CRISPRa

CAT#: GA116366

DHFR2 CRISPRa kit - CRISPR gene activation of human dihydrofolate reductase 2


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol DHFR2
Locus ID 200895
Kit Components

GA116366G1, DHFR2 gRNA vector 1 in pCas-Guide-CRISPRa

GA116366G2, DHFR2 gRNA vector 2 in pCas-Guide-CRISPRa

GA116366G3, DHFR2 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001195643, NM_176815
Synonyms DHFRP4
Summary Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR. [UniProtKB/Swiss-Prot Function]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.