Human DHFRL1 (DHFR2) activation kit by CRISPRa
CAT#: GA116366
DHFR2 CRISPRa kit - CRISPR gene activation of human dihydrofolate reductase 2
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | DHFR2 |
Locus ID | 200895 |
Kit Components | GA116366G1, DHFR2 gRNA vector 1 in pCas-Guide-CRISPRa GA116366G2, DHFR2 gRNA vector 2 in pCas-Guide-CRISPRa GA116366G3, DHFR2 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001195643, NM_176815 |
Synonyms | DHFRP4 |
Summary | Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR. [UniProtKB/Swiss-Prot Function] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN408452 | DHFR2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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