Human FLCN activation kit by CRISPRa

CAT#: GA116378

FLCN CRISPRa kit - CRISPR gene activation of human folliculin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FLCN
• Locus ID: 201163
• Kit Components:

  GA116378G1, FLCN gRNA vector 1 in pCas-Guide-CRISPRa

  GA116378G2, FLCN gRNA vector 2 in pCas-Guide-CRISPRa

  GA116378G3, FLCN gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_144606, NM_144997, NM_001353229, NM_001353230, NM_001353231
• Synonyms: BHD; FLCL
• Summary: This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]