Human TAPT1 activation kit by CRISPRa

CAT#: GA116412

TAPT1 CRISPRa kit - CRISPR gene activation of human transmembrane anterior posterior transformation 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TAPT1
• Locus ID: 202018
• Kit Components:

  GA116412G1, TAPT1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116412G2, TAPT1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116412G3, TAPT1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_153365
• Synonyms: CMVFR
• Summary: This gene encodes a highly conserved protein that localizes to the centrosome and/or ciliary basal body. Mutations in this gene disrupt Golgi morphology and trafficking and normal primary cilium formation and these mutations are congenitally manifested by severe undermineralization of the intra-uterine skeleton. A mutation in the mouse ortholog of this gene results in homeotic, posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants. In mouse, this gene is thought to function downstream of homeobox C8 to transduce extracellular patterning information during axial skeleton development. [provided by RefSeq, Jan 2017]