Human UNC5B activation kit by CRISPRa

CAT#: GA116509

UNC5B CRISPRa kit - CRISPR gene activation of human unc-5 netrin receptor B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UNC5B
• Locus ID: 219699
• Kit Components:

  GA116509G1, UNC5B gRNA vector 1 in pCas-Guide-CRISPRa

  GA116509G2, UNC5B gRNA vector 2 in pCas-Guide-CRISPRa

  GA116509G3, UNC5B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001244889, NM_170744
• Synonyms: p53RDL1; UNC5H2
• Summary: This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]