Human GPR136 (OPN5) activation kit by CRISPRa

CAT#: GA116611

OPN5 CRISPRa kit - CRISPR gene activation of human opsin 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: OPN5
• Locus ID: 221391
• Kit Components:

  GA116611G1, OPN5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116611G2, OPN5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116611G3, OPN5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001030051, NM_181744, NR_033806
• Synonyms: NEUROPSIN; opsin 5; OTTHUMP00000016565; OTTHUMP00000039910; PGR12; TMEM13; transmembrane protein 13
• Summary: Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This opsin gene is expressed in the eye, brain, testes, and spinal cord. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other seven-exon opsin genes, this family member may encode a protein with photoisomerase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]