Human KIF6 activation kit by CRISPRa

CAT#: GA116619

KIF6 CRISPRa kit - CRISPR gene activation of human kinesin family member 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KIF6
• Locus ID: 221458
• Kit Components:

  GA116619G1, KIF6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116619G2, KIF6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116619G3, KIF6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001289020, NM_001289021, NM_001289024, NM_145027, NM_001351503, NM_001351566
• Synonyms: C6orf102; dJ137F1.4; dJ188D3.1; dJ1043E3.1
• Summary: This gene encodes a member of a family of molecular motors which are involved in intracellular transport of protein complexes, membrane organelles, and messenger ribonucleic acid along microtubules. Kinesins function as homodimeric molecules with two N-terminal head domains that move along microtubules and two C-terminal tail domains that interact with the transported cargo, either directly or indirectly, through adapter molecules. This gene is ubiquitously expressed in coronary arteries and other vascular tissue. A naturally occurring mutation in this gene is associated with coronary heart disease. [provided by RefSeq, May 2017]