Human PHACTR1 activation kit by CRISPRa

CAT#: GA116634

PHACTR1 CRISPRa kit - CRISPR gene activation of human phosphatase and actin regulator 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PHACTR1
• Locus ID: 221692
• Kit Components:

  GA116634G1, PHACTR1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116634G2, PHACTR1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116634G3, PHACTR1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001242648, NM_001322308, NM_001322309, NM_001322310, NM_001322311, NM_001322312, NM_001322313, NM_001322314, NM_030948
• Synonyms: dJ257A7.2; RPEL; RPEL1
• Summary: The protein encoded by this gene is a member of the phosphatase and actin regulator family of proteins. This family member can bind actin and regulate the reorganization of the actin cytoskeleton. It plays a role in tubule formation and in endothelial cell survival. Polymorphisms in this gene are associated with susceptibility to myocardial infarction, coronary artery disease and cervical artery dissection. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]