Human PRPS1L1 activation kit by CRISPRa

CAT#: GA116641

PRPS1L1 CRISPRa kit - CRISPR gene activation of human phosphoribosyl pyrophosphate synthetase 1 like 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRPS1L1
• Locus ID: 221823
• Kit Components:

  GA116641G1, PRPS1L1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116641G2, PRPS1L1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116641G3, PRPS1L1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_175886
• Synonyms: PRPS1; PRPS3; PRPSL; PRS-III
• Summary: This intronless gene is specifically expressed in the testis, and encodes a protein that is highly homologous to the two subunits of phosphoribosylpyrophosphate synthetase encoded by human X-linked genes, PRPS1 and PRPS2. These enzymes convert pyrimidine, purine or pyridine bases to the corresponding ribonucleoside monophosphates. In vitro transcription/translation and site-directed mutagenesis studies indicate that translation of this mRNA initiates exclusively at a non-AUG (ACG) codon. [provided by RefSeq, Jul 2008]