Human VGLUT3 (SLC17A8) activation kit by CRISPRa

CAT#: GA116722

SLC17A8 CRISPRa kit - CRISPR gene activation of human solute carrier family 17 member 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC17A8
• Locus ID: 246213
• Kit Components:

  GA116722G1, SLC17A8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116722G2, SLC17A8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116722G3, SLC17A8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145288, NM_139319
• Synonyms: DFNA25; VGLUT3
• Summary: This gene encodes a vesicular glutamate transporter. The encoded protein transports the neurotransmitter glutamate into synaptic vesicles before it is released into the synaptic cleft. Mutations in this gene are the cause of autosomal-dominant nonsyndromic type 25 deafness. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]