Human MSRB3 activation kit by CRISPRa

CAT#: GA116758

MSRB3 CRISPRa kit - CRISPR gene activation of human methionine sulfoxide reductase B3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MSRB3
• Locus ID: 253827
• Kit Components:

  GA116758G1, MSRB3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116758G2, MSRB3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116758G3, MSRB3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001031679, NM_001193460, NM_001193461, NM_198080
• Synonyms: DFNB74
• Summary: The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula. [provided by RefSeq, Jul 2010]