Human GARNL1 (RALGAPA1) activation kit by CRISPRa

CAT#: GA116762

RALGAPA1 CRISPRa kit - CRISPR gene activation of human Ral GTPase activating protein catalytic alpha subunit 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RALGAPA1
• Locus ID: 253959
• Kit Components:

  GA116762G1, RALGAPA1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116762G2, RALGAPA1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116762G3, RALGAPA1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001283043, NM_001283044, NM_001330075, NM_001346243, NM_001346245, NM_001346246, NM_001346247, NM_001346248, NM_001346249, NM_014990, NM_194301
• Synonyms: GARNL1; GRIPE; p240; RalGAPalpha1; TULIP1
• Summary: This gene encodes a major subunit of the RAL-GTPase activating protein. A similar protein in mouse binds E12, a transcriptional regulator of immunoglobulin genes. The mouse protein also functions in skeletal muscle by binding to the regulatory 14-3-3 proteins upon stimulation with insulin or muscle contraction. A pseudogene of this gene has been identified on chromosome 9. [provided by RefSeq, Oct 2016]