Human POLDIP1 (KCTD13) activation kit by CRISPRa

CAT#: GA116763

KCTD13 CRISPRa kit - CRISPR gene activation of human potassium channel tetramerization domain containing 13

SDS

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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol KCTD13
Locus ID 253980
Kit Components

GA116763G1, KCTD13 gRNA vector 1 in pCas-Guide-CRISPRa

GA116763G2, KCTD13 gRNA vector 2 in pCas-Guide-CRISPRa

GA116763G3, KCTD13 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058
Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_178863, NR_110933
Synonyms BACURD1; FKSG86; hBACURD1; PDIP1; POLDIP1
Summary Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission (PubMed:19782033). The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome (PubMed:19782033) Degradation of RHOA regulates the actin cytoskeleton and promotes synaptic transmission. [UniProtKB/Swiss-Prot Function]

Other Versions

SKU Description Size Price
KN406944 KCTD13 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.