Human Protein cornichon homolog 2 (CNIH2) activation kit by CRISPRa

CAT#: GA116780

CNIH2 CRISPRa kit - CRISPR gene activation of human cornichon family AMPA receptor auxiliary protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CNIH2
• Locus ID: 254263
• Kit Components:

  GA116780G1, CNIH2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116780G2, CNIH2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116780G3, CNIH2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_182553, NR_073078, NR_073079
• Synonyms: CNIH-2; Cnil
• Summary: The protein encoded by this gene is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype. AMPA receptors mediate fast synaptic neurotransmission in the central nervous system. This protein has been reported to interact with the Type I AMPA receptor regulatory protein isoform gamma-8 to control assembly of hippocampal AMPA receptor complexes, thereby modulating receptor gating and pharmacology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]