Human MCM9 activation kit by CRISPRa

CAT#: GA116785

MCM9 CRISPRa kit - CRISPR gene activation of human minichromosome maintenance 9 homologous recombination repair factor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MCM9
• Locus ID: 254394
• Kit Components:

  GA116785G1, MCM9 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116785G2, MCM9 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116785G3, MCM9 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_017696, NM_153255
• Synonyms: C6orf61; dJ329L24.1; dJ329L24.3; MCMDC1; ODG4
• Summary: The protein encoded by this gene is a member of the mini-chromosome maintenance (MCM) protein family that are essential for the initiation of eukaryotic genome replication. Binding of this protein to chromatin has been shown to be a pre-requisite for recruiting the MCM2-7 helicase to DNA replication origins. This protein also binds, and is a positive regulator of, the chromatin licensing and DNA replication factor 1, CDT1. [provided by RefSeq, Nov 2010]