Human TAC4 activation kit by CRISPRa

CAT#: GA116808

TAC4 CRISPRa kit - CRISPR gene activation of human tachykinin 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TAC4
• Locus ID: 255061
• Kit Components:

  GA116808G1, TAC4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116808G2, TAC4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116808G3, TAC4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001077503, NM_001077504, NM_001077505, NM_001077506, NM_170685
• Synonyms: EK; HK-1; HK1; PPT-C
• Summary: This gene is a member of the tachykinin family of neurotransmitter-encoding genes. Tachykinin proteins are cleaved into small, secreted peptides that activate members of a family of receptor proteins. The products of this gene preferentially activate tachykinin receptor 1, and are thought to regulate peripheral endocrine and paracrine functions including blood pressure, the immune system, and endocrine gland secretion. The products of this gene lack a dibasic cleavage site found in other tachykinin proteins. Consequently, the nature of the cleavage products generated in vivo remains to be determined. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]