Human NCR3 activation kit by CRISPRa

CAT#: GA116904

NCR3 CRISPRa kit - CRISPR gene activation of human natural cytotoxicity triggering receptor 3


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol NCR3
Locus ID 259197
Kit Components

GA116904G1, NCR3 gRNA vector 1 in pCas-Guide-CRISPRa

GA116904G2, NCR3 gRNA vector 2 in pCas-Guide-CRISPRa

GA116904G3, NCR3 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001145466, NM_001145467, NM_147130
Synonyms 1C7; CD337; LY117; MALS; NKp30
Summary The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.