Human IL4I1 activation kit by CRISPRa

CAT#: GA116927

IL4I1 CRISPRa kit - CRISPR gene activation of human interleukin 4 induced 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IL4I1
• Locus ID: 259307
• Kit Components:

  GA116927G1, IL4I1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116927G2, IL4I1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116927G3, IL4I1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001258017, NM_001258018, NM_152899, NM_172374, NR_047577
• Synonyms: FIG1; LAAO; LAO
• Summary: This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]