Human CYP4X1 activation kit by CRISPRa

CAT#: GA116929

CYP4X1 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 4 subfamily X member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CYP4X1
• Locus ID: 260293
• Kit Components:

  GA116929G1, CYP4X1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116929G2, CYP4X1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116929G3, CYP4X1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001320289, NM_001320290, NM_178033
• Synonyms: CYPIVX1
• Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes and is located within a cluster of genes belonging to this superfamily on chromosome 1. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]