Human TIPRL activation kit by CRISPRa

CAT#: GA116935

TIPRL CRISPRa kit - CRISPR gene activation of human TOR signaling pathway regulator

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TIPRL
• Locus ID: 261726
• Kit Components:

  GA116935G1, TIPRL gRNA vector 1 in pCas-Guide-CRISPRa

  GA116935G2, TIPRL gRNA vector 2 in pCas-Guide-CRISPRa

  GA116935G3, TIPRL gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001031800, NM_152902
• Synonyms: TIP; TIP41
• Summary: TIPRL is an inhibitory regulator of protein phosphatase-2A (PP2A) (see PPP2CA; MIM 176915), PP4 (see PPP4C; MIM 602035), and PP6 (see PPP6C; MIM 612725) (McConnell et al., 2007 [PubMed 17384681]). [supplied by OMIM, Nov 2010]