Human IL28A (IFNL2) activation kit by CRISPRa

CAT#: GA116961

IFNL2 CRISPRa kit - CRISPR gene activation of human interferon lambda 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IFNL2
• Locus ID: 282616
• Kit Components:

  GA116961G1, IFNL2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116961G2, IFNL2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116961G3, IFNL2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_172138
• Synonyms: IL-28A; IL28A
• Summary: This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]