Human BLOC1S2 activation kit by CRISPRa

CAT#: GA116975

BLOC1S2 CRISPRa kit - CRISPR gene activation of human biogenesis of lysosomal organelles complex 1 subunit 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BLOC1S2
• Locus ID: 282991
• Kit Components:

  GA116975G1, BLOC1S2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116975G2, BLOC1S2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116975G3, BLOC1S2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001001342, NM_001282436, NM_001282437, NM_001282438, NM_001282439, NM_173809, NR_046296, NR_046314, NR_046315
• Synonyms: BLOS2; BORCS2; CEAP; CEAP11
• Summary: This gene encodes a protein with multiple functions. The encoded protein has been found in association with the centrosome, shown to co-localize with gamma-tubulin, and also found to be one of the proteins in the BLOC-1 complex which functions in the formation of lysosome-related organelles. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]