Human SLC46A3 activation kit by CRISPRa

CAT#: GA117037

SLC46A3 CRISPRa kit - CRISPR gene activation of human solute carrier family 46 member 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC46A3
• Locus ID: 283537
• Kit Components:

  GA117037G1, SLC46A3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA117037G2, SLC46A3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA117037G3, SLC46A3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001135919, NM_181785, NM_001347960
• Synonyms: FKSG16
• Summary: The protein encoded by this gene is a member of a transmembrane protein family that transports small molecules across membranes. The encoded protein has been found in lysosomal membranes, where it can transport catabolites from the lysosomes to the cytoplasm. This protein has been shown to be an effective transporter of the cytotoxic drug maytansine, which is used in antibody-based targeting of cancer cells. [provided by RefSeq, Dec 2016]