Human NPW activation kit by CRISPRa

CAT#: GA117065

NPW CRISPRa kit - CRISPR gene activation of human neuropeptide W

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NPW
• Locus ID: 283869
• Kit Components:

  GA117065G1, NPW gRNA vector 1 in pCas-Guide-CRISPRa

  GA117065G2, NPW gRNA vector 2 in pCas-Guide-CRISPRa

  GA117065G3, NPW gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001099456
• Synonyms: L8; L8C; PPL8; PPNPW
• Summary: The product of this gene is processed into 23- and 30-amino acid neuropeptides that bind and activate two G-protein coupled receptors in the central nervous system. The neuropeptides have been shown to enhance cortisol secretion from adrenal cells through the adenylate cyclase/protein kinase A signaling cascade. The preproprotein is translated using a non-AUG initiation codon that is inferred from analyses of the mouse ortholog. [provided by RefSeq, Jul 2008]