Human NEK8 activation kit by CRISPRa

CAT#: GA117093

NEK8 CRISPRa kit - CRISPR gene activation of human NIMA related kinase 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NEK8
• Locus ID: 284086
• Kit Components:

  GA117093G1, NEK8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA117093G2, NEK8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA117093G3, NEK8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_178170
• Synonyms: JCK; NEK12A; NPHP9; RHPD2
• Summary: This gene encodes a member of the serine/threionine protein kinase family related to NIMA (never in mitosis, gene A) of Aspergillus nidulans. The encoded protein may play a role in cell cycle progression from G2 to M phase. Mutations in the related mouse gene are associated with a disease phenotype that closely parallels the juvenile autosomal recessive form of polycystic kidney disease in humans. [provided by RefSeq, Jul 2008]