Human PIGW activation kit by CRISPRa

CAT#: GA117094

PIGW CRISPRa kit - CRISPR gene activation of human phosphatidylinositol glycan anchor biosynthesis class W

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PIGW
• Locus ID: 284098
• Kit Components:

  GA117094G1, PIGW gRNA vector 1 in pCas-Guide-CRISPRa

  GA117094G2, PIGW gRNA vector 2 in pCas-Guide-CRISPRa

  GA117094G3, PIGW gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_178517, NM_001346754, NM_001346755
• Synonyms: Gwt1; HPMRS5
• Summary: The protein encoded by this gene is an inositol acyltransferase that acylates the inositol ring of phosphatidylinositol. This occurs in the endoplasmic reticulum and is a step in the biosynthesis of glycosylphosphatidylinositol (GPI), which anchors many cell surface proteins to the membrane. Defects in this gene are a cause of the age-dependent epileptic encephalopathy West syndrome as well as a syndrome exhibiting hyperphosphatasia and cognitive disability (HPMRS5). [provided by RefSeq, Jul 2017]