Human CXCL17 activation kit by CRISPRa

CAT#: GA117124

CXCL17 CRISPRa kit - CRISPR gene activation of human C-X-C motif chemokine ligand 17

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CXCL17
• Locus ID: 284340
• Kit Components:

  GA117124G1, CXCL17 gRNA vector 1 in pCas-Guide-CRISPRa

  GA117124G2, CXCL17 gRNA vector 2 in pCas-Guide-CRISPRa

  GA117124G3, CXCL17 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_198477, NR_133910
• Synonyms: Dcip1; DMC; UNQ473; VCC-1; VCC1
• Summary: The protein encoded by this gene is a mucosal chemokine that attracts immature dendritic cells and blood monocytes to the lungs. The encoded protein also promotes tumorigenesis through an angiogenic activity. Finally, this protein exhibits strong antimicrobial activity against E. coli, S. aureus, Salmonella, P. aeruginosa, and C. albicans. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015]