Human SUMF1 activation kit by CRISPRa

CAT#: GA117217

SUMF1 CRISPRa kit - CRISPR gene activation of human sulfatase modifying factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SUMF1
• Locus ID: 285362
• Kit Components:

  GA117217G1, SUMF1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA117217G2, SUMF1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA117217G3, SUMF1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001164674, NM_001164675, NM_182760
• Synonyms: AAPA3037; FGE; UNQ3037
• Summary: This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]