Human KCNK18 activation kit by CRISPRa

CAT#: GA117374

KCNK18 CRISPRa kit - CRISPR gene activation of human potassium two pore domain channel subfamily K member 18

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCNK18
• Locus ID: 338567
• Kit Components:

  GA117374G1, KCNK18 gRNA vector 1 in pCas-Guide-CRISPRa

  GA117374G2, KCNK18 gRNA vector 2 in pCas-Guide-CRISPRa

  GA117374G3, KCNK18 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_181840
• Synonyms: K2p18.1; MGR13; TRESK; TRESK-2; TRESK2; TRIK
• Summary: Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains and the encoded protein functions as an outward rectifying potassium channel. A mutation in this gene has been found to be associated with migraine with aura. [provided by RefSeq, Jan 2011]