Human NAT8L activation kit by CRISPRa

CAT#: GA117454

NAT8L CRISPRa kit - CRISPR gene activation of human N-acetyltransferase 8 like

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NAT8L
• Locus ID: 339983
• Kit Components:

  GA117454G1, NAT8L gRNA vector 1 in pCas-Guide-CRISPRa

  GA117454G2, NAT8L gRNA vector 2 in pCas-Guide-CRISPRa

  GA117454G3, NAT8L gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_178557
• Synonyms: CML3; NACED; NAT8-LIKE
• Summary: This gene encodes a single-pass membrane protein, which contains a conserved sequence of the GCN5 or NAT superfamily of N-acetyltransferases and is a member of the N-acyltransferase (NAT) superfamily. This protein is a neuron-specific protein and is the N-acetylaspartate (NAA) biosynthetic enzyme, catalyzing the NAA synthesis from L-aspartate and acetyl-CoA. NAA is a major storage and transport form of acetyl coenzyme A specific to the nervous system. The gene mutation results in primary NAA deficiency (hypoacetylaspartia). [provided by RefSeq, Dec 2010]