Human RSPO2 activation kit by CRISPRa

CAT#: GA117479

RSPO2 CRISPRa kit - CRISPR gene activation of human R-spondin 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RSPO2
• Locus ID: 340419
• Kit Components:

  GA117479G1, RSPO2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA117479G2, RSPO2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA117479G3, RSPO2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001282863, NM_001317942, NM_178565
• Synonyms: CRISTIN2
• Summary: This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]