Human Gliomedin (GLDN) activation kit by CRISPRa

CAT#: GA117528

GLDN CRISPRa kit - CRISPR gene activation of human gliomedin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GLDN
• Locus ID: 342035
• Kit Components:

  GA117528G1, GLDN gRNA vector 1 in pCas-Guide-CRISPRa

  GA117528G2, GLDN gRNA vector 2 in pCas-Guide-CRISPRa

  GA117528G3, GLDN gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_181789, NM_001330297
• Synonyms: CLOM; COLM; CRG-L2; CRGL2; UNC-112
• Summary: This gene encodes a protein that contains olfactomedin-like and collagen-like domains. The encoded protein, which exists in both transmembrane and secreted forms, promotes formation of the nodes of Ranvier in the peripheral nervous system. Mutations in this gene cause a form of lethal congenital contracture syndrome in human patients. Autoantibodies to the encoded protein have been identified in sera form patients with multifocal motor neuropathy. [provided by RefSeq, May 2017]