Human RD3 activation kit by CRISPRa

CAT#: GA117558

RD3 CRISPRa kit - CRISPR gene activation of human retinal degeneration 3, GUCY2D regulator

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RD3
• Locus ID: 343035
• Kit Components:

  GA117558G1, RD3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA117558G2, RD3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA117558G3, RD3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001164688, NM_183059
• Synonyms: C1orf36; LCA12
• Summary: This gene encodes a retinal protein that is associated with promyelocytic leukemia-gene product (PML) bodies in the nucleus. Mutations in this gene cause Leber congenital amaurosis type 12, a disease that results in retinal degeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]