Human RSPO4 activation kit by CRISPRa

CAT#: GA117579

RSPO4 CRISPRa kit - CRISPR gene activation of human R-spondin 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RSPO4
• Locus ID: 343637
• Kit Components:

  GA117579G1, RSPO4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA117579G2, RSPO4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA117579G3, RSPO4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001029871, NM_001040007
• Synonyms: C20orf182; CRISTIN4
• Summary: This gene encodes a member of the R-spondin family of proteins that share a common domain organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded protein may be involved in activation of Wnt/beta-catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]