Human KIF24 activation kit by CRISPRa

CAT#: GA117640

KIF24 CRISPRa kit - CRISPR gene activation of human kinesin family member 24

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KIF24
• Locus ID: 347240
• Kit Components:

  GA117640G1, KIF24 gRNA vector 1 in pCas-Guide-CRISPRa

  GA117640G2, KIF24 gRNA vector 2 in pCas-Guide-CRISPRa

  GA117640G3, KIF24 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_194313
• Synonyms: bA571F15.4; C9orf48
• Summary: This gene encodes a member of the kinesin superfamily of microtubule-based motor proteins which are involved in the intracellular transport of membranous organelles, protein complexes, and mRNAs. They also play critical roles in mitosis, morphogenesis, and signal transduction. The encoded protein contains an N-terminal sterile alpha motif (SAM) domain and an ATP-binding kinesin motor domain. It binds centriolar coiled coil protein 110 and centrosomal protein 97 and localizes to the mother centriole to regulate ciliogenesis by controlling microtubule polymerization. [provided by RefSeq, Mar 2017]