Human HCN1 activation kit by CRISPRa

CAT#: GA117691

HCN1 CRISPRa kit - CRISPR gene activation of human hyperpolarization activated cyclic nucleotide gated potassium channel 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HCN1
• Locus ID: 348980
• Kit Components:

  GA117691G1, HCN1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA117691G2, HCN1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA117691G3, HCN1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_021072
• Synonyms: BCNG-1; BCNG1; EIEE24; HAC-2
• Summary: The membrane protein encoded by this gene is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize or heterodimerize with other pore-forming subunits to form a potassium channel. This channel may act as a receptor for sour tastes. [provided by RefSeq, Oct 2011]