Human NMNAT3 activation kit by CRISPRa

CAT#: GA117697

NMNAT3 CRISPRa kit - CRISPR gene activation of human nicotinamide nucleotide adenylyltransferase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NMNAT3
• Locus ID: 349565
• Kit Components:

  GA117697G1, NMNAT3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA117697G2, NMNAT3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA117697G3, NMNAT3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001200047, NM_001320510, NM_001320511, NM_001320512, NM_001320513, NM_178177, NM_001363968
• Synonyms: FKSG76; PNAT-3; PNAT3
• Summary: This gene encodes a member of the nicotinamide/nicotinic acid mononucleotide adenylyltransferase family. These enzymes use ATP to catalyze the synthesis of nicotinamide adenine dinucleotide or nicotinic acid adenine dinucleotide from nicotinamide mononucleotide or nicotinic acid mononucleotide, respectively. The encoded protein is localized to mitochondria and may also play a neuroprotective role as a molecular chaperone. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]