Human RAET1G activation kit by CRISPRa

CAT#: GA117705

RAET1G CRISPRa kit - CRISPR gene activation of human retinoic acid early transcript 1G

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RAET1G
• Locus ID: 353091
• Kit Components:

  GA117705G1, RAET1G gRNA vector 1 in pCas-Guide-CRISPRa

  GA117705G2, RAET1G gRNA vector 2 in pCas-Guide-CRISPRa

  GA117705G3, RAET1G gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001001788, NR_130110
• Synonyms: ULBP5
• Summary: This gene encodes a member of the major histocompatibility complex (MHC) class I family of proteins. Although the encoded protein includes C-terminal transmembrane and cytoplasmic domains, proteolytic processing results in the removal of these domains and subsequent tethering to the plasma membrane by a glycosylphosphatidylinositol (GPI)-anchor. The encoded protein is one of several related ligands of the natural killer group 2, member D (NKG2D) receptor, which functions as an activating receptor in innate and adaptive immunity. This gene is present in a gene cluster on chromosome 6. [provided by RefSeq, Jul 2015]