Human RAD26L (ERCC6L2) activation kit by CRISPRa

CAT#: GA117832

ERCC6L2 CRISPRa kit - CRISPR gene activation of human ERCC excision repair 6 like 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ERCC6L2
• Locus ID: 375748
• Kit Components:

  GA117832G1, ERCC6L2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA117832G2, ERCC6L2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA117832G3, ERCC6L2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001010895, NM_020207
• Synonyms: BMFS2; C9orf102; RAD26L; SR278
• Summary: This gene encodes a member of the Snf2 family of helicase-like proteins. The encoded protein may play a role in DNA repair and mitochondrial function. Mutations in this gene have been associated with bone marrow failure syndrome 2. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Apr 2014]