Human NPSR1 activation kit by CRISPRa

CAT#: GA117878

NPSR1 CRISPRa kit - CRISPR gene activation of human neuropeptide S receptor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NPSR1
• Locus ID: 387129
• Kit Components:

  GA117878G1, NPSR1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA117878G2, NPSR1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA117878G3, NPSR1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001300933, NM_001300934, NM_001300935, NM_207172, NM_207173
• Synonyms: ASRT2; GPR154; GPRA; NPSR; PGR14; VRR1
• Summary: This gene encodes a member of the vasopressin/oxytocin subfamily of G protein-coupled receptors. The encoded membrane protein acts as a receptor for neuropeptide S and affects a variety of cellular processes through its signaling. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Polymorphisms in this gene have also been associated with asthma susceptibility, panic disorders, inflammatory bowel disease, and rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]