Human MAFA activation kit by CRISPRa

CAT#: GA118070

MAFA CRISPRa kit - CRISPR gene activation of human MAF bZIP transcription factor A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MAFA
• Locus ID: 389692
• Kit Components:

  GA118070G1, MAFA gRNA vector 1 in pCas-Guide-CRISPRa

  GA118070G2, MAFA gRNA vector 2 in pCas-Guide-CRISPRa

  GA118070G3, MAFA gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_201589
• Synonyms: hMafA; RIPE3b1
• Summary: MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS; MIM 176730) (Olbrot et al., 2002 [PubMed 12011435]). [supplied by OMIM, Mar 2008]